Underpowered or negative? A crucial distinction. Reply to Dollerup OL, Treebak JT, Jessen N [letter]

Affiliations

¹ Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands.
² Laboratory Genetic Metabolic Diseases, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
³ Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands. p.schrauwen@maastrichtuniversity.nl.

Comment

Niels J Connell et al. Diabetologia. 2019 Jun.

. 2019 Jun;62(6):1096.

doi: 10.1007/s00125-019-4868-3. Epub 2019 Apr 13.

¹ Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands.
² Laboratory Genetic Metabolic Diseases, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
³ Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands. p.schrauwen@maastrichtuniversity.nl.

No abstract available

Keywords: Clinical trial; Human; NAD+ metabolism.

Comment on

NAD⁺ metabolism as a target for metabolic health: have we found the silver bullet?
Connell NJ, Houtkooper RH, Schrauwen P. Connell NJ, et al. Diabetologia. 2019 Jun;62(6):888-899. doi: 10.1007/s00125-019-4831-3. Epub 2019 Feb 16. Diabetologia. 2019. PMID: 30772929 Free PMC article. Review.
Underpowered or negative? A crucial distinction.
Dollerup OL, Treebak JT, Jessen N. Dollerup OL, et al. Diabetologia. 2019 Jun;62(6):1094-1095. doi: 10.1007/s00125-019-4853-x. Epub 2019 Mar 25. Diabetologia. 2019. PMID: 30911774 No abstract available.

1. Dollerup OL, Treebak JT, Jessen N (2019) Underpowered or negative? A crucial distinction. Diabetologia. https://doi.org/10.1007/s00125-019-4853-x
1. Connell NJ, Houtkooper RH, Schrauwen P (2019) NAD⁺ metabolism as a target for metabolic health: have we found the silver bullet? Diabetologia. https://doi.org/10.1007/s00125-019-4831-3
1. Dollerup OL, Christensen B, Svart M et al (2018) A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr 108(2):343–353. https://doi.org/10.1093/ajcn/nqy132 - DOI - PubMed