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. 2019 Dec;23(12):4441-4448.
doi: 10.1007/s00784-019-02892-2. Epub 2019 Apr 15.

Severity of oral lichen planus and oral lichenoid lesions is associated with anxiety

Miriane Lucindo Zucoloto  1 , Matheus Eiji Warikoda Shibakura  2 , Jefferson Veronezi Pavanin  2 , Fernanda Teixeira Garcia  2 , Paulo Sérgio da Silva Santos  3 , Aloizio Premoli Maciel  3 , Camila de Barros Gallo  4 , Nathalia Vilela Souza  4 , Lara Maria Alencar Ramos Innocentini  2   5 , Janaina Silva Martins Humberto  2 , Ana Carolina Fragoso Motta  6
Affiliations

Severity of oral lichen planus and oral lichenoid lesions is associated with anxiety

Miriane Lucindo Zucoloto et al. Clin Oral Investig. 2019 Dec.

Abstract

Objectives: Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are chronic inflammatory diseases whose symptoms can impair patient's quality of life (QoL). Psychological factors seem to play an important role in these diseases. This study aimed to determine the impact of oral health and anxiety levels on the QoL of patients with OLP and OLL.

Patients and methods: This was a cross-sectional study composed of OLP and OLL patients and a control group matched by age and sex with no autoimmune/inflammatory or malignant oral lesions. Anxiety levels and oral health impact on QoL were assessed using the Hamilton Anxiety Scale (HAM-A) and the Oral Health Impact Profile-14 (OHIP-14), respectively. The instruments were filled through personal interview before starting the treatment for oral lesions.

Results: A total of 87 patients diagnosed with OLP (n = 45) and OLL (n = 42), and 87 controls were included in the study. Statistical differences were observed for the psychic and somatic anxiety dimensions between severities of diseases. Patients with OLP or OLL had higher scores for the OHIP-14 dimensions physiological discomfort and social limitation compared with controls. In addition, higher scores for physical pain, physical disability, social disability, and handicap were detected among patients with greater severity.

Conclusion: Greater severity of OLP and OLL seems to be associated with increased levels of anxiety, higher scores of oral health impact profile, and decreased QoL.

Clinical relevance: Patients with severe OLP/OLL may benefit from additional therapeutic treatments, such as psychological and/or psychiatric management, concomitant to treatment specific to oral lesions.

Keywords: Anxiety; Oral lichen planus; Oral lichenoid lesions; Quality of life.

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