doi: 10.1128/mcb.6.12.4763-4766.1986.
DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae
- PMID: 3099172
- PMCID: PMC367265
- DOI: 10.1128/mcb.6.12.4763-4766.1986
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DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae
Mol Cell Biol.
1986 Dec.
Abstract
We showed by immunofluorescence that the procaryotic DNA-binding protein LexA and a chimeric protein that contains the DNA-binding portion of LexA (amino acids 1 to 87) and a large portion (amino acids 74 to 881) of the Saccharomyces cerevisiae positive regulatory GAL4 protein (GAL4 gene product) are not preferentially localized in the nucleus in S. cerevisiae.
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