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Review
. 2013 Aug 19;2(4):177-180.
doi: 10.1002/cld.220. eCollection 2013 Aug.

Hepatitis C virus: Management of recurrent disease

Affiliations
Review

Hepatitis C virus: Management of recurrent disease

Elizabeth C Verna. Clin Liver Dis (Hoboken). .
No abstract available

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Figures

Figure 1
Figure 1
After the initiation of HCV treatment, survival is higher for HCV‐positive LT recipients who achieve SVR (with 1‐, 3‐, and 5‐year survival rates of 96%, 94%, and 94%, respectively) versus nonresponders (97%, 73%, and 68%, respectively; P = 0.012, log‐rank test). Reprinted with permission from Journal of Hepatology.7 Copyright 2012, Elsevier.
Figure 2
Figure 2
(A) Dose‐normalized mean (standard deviation) blood concentration–time profiles for cyclosporine after the administration of cyclosporine alone or with telaprevir (a log‐linear scale). (B) Dose‐normalized mean (standard deviation) blood concentration–time profiles for tacrolimus after the administration of tacrolimus alone or with telaprevir (a log‐linear scale). Reprinted with permission from Hepatology.11 Copyright 2011, American Association for the Study of Liver Diseases.
Figure 3
Figure 3
The cumulative hazard of graft failure due to recurrent disease is higher in patients who receive tacrolimus as their primary immunosuppression versus patients who receive cyclosporine (hazard ratio = 1.4, P = 0.007) in the United Network for Organ Sharing database. Reprinted with permission from American Journal of Transplantation.24 Copyright 2011, American Society of Transplantation and American Society of Transplant Surgeons.

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