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. 2018 Dec 21;5(1):37-43.
doi: 10.1016/j.cdtm.2018.10.001. eCollection 2019 Mar.

Association between timing of peritoneal dialysis initiation and mortality in end-stage renal disease

Yuan Peng  1   2 , Xiao Yang  1   2 , Wei Chen  1   2 , Xue-Qing Yu  1   2
Affiliations

Association between timing of peritoneal dialysis initiation and mortality in end-stage renal disease

Yuan Peng et al. Chronic Dis Transl Med. .

Abstract

Despite the widespread use of chronic dialysis for end-stage renal disease (ESRD), there is no consensus on the optimal timing of initiating renal replacement therapy. Over the past decade, a worldwide trend toward increasing glomerular filtration rate at the initiation of dialysis has been noted. However, available data indicate that early dialysis has no survival benefit or is harmful. Peritoneal dialysis (PD) is one alternative for ESRD and has potential survival factors different from those of hemodialysis. The association between the timing of PD initiation and survival is unclear. This review examines the effect of the timing of dialysis on clinical outcomes in PD patients.

Keywords: Glomerular filtration rate (GFR); Initiation; Mortality; Peritoneal dialysis (PD).

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