Elevated Human Crimean-Congo Hemorrhagic Fever Virus Seroprevalence in Khashm el Girba, Eastern Sudan
- PMID: 30994100
- PMCID: PMC6553917
- DOI: 10.4269/ajtmh.18-0977
Elevated Human Crimean-Congo Hemorrhagic Fever Virus Seroprevalence in Khashm el Girba, Eastern Sudan
Abstract
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease that can evolve into deadly hemorrhagic fever and that is endemic in many parts of Europe, Middle East, Central Asia, and Africa. Because of several reports about CCHF outbreaks in the south of Sudan during the last years, we examined in this study if unrecognized CCHF-V infections also occurred in the eastern and central parts of the country. The study examined the seroprevalence of CCHF virus infection in 464 sera from three regions of Sudan without previous reports of CCHF infection. The total CCHF virus seroprevalence was 2.6% (12 sera). The percentage was significantly elevated (7.5%) in sera from Khashm el Girba in eastern Sudan. The population in this area should be educated about the risk of disease transmission and how to avoid the infection. Health-care providers should be informed about the disease to identify possible cases and to prevent nosocomial transmission.
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References
-
- Kuhn JH, Peters CJ, 2014. Arthropod-borne and rodent-borne virus infections. Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J, eds. Harrison's Principles of Internal Medicine New York, NY: McGraw-Hill, 1617–1633.
-
- Chapman LE, Wilson ML, Hall DB, LeGuenno B, Dykstra EA, Ba K, Fisher-Hoch SP, 1991. Risk factors for Crimean-Congo hemorrhagic fever in rural northern Senegal. J Infect Dis 164: 686–692. - PubMed
-
- Watts DM, el-Tigani A, Botros BA, Salib AW, Olson JG, McCarthy M, Ksiazek TG, 1994. Arthropod-borne viral infections associated with a fever outbreak in the northern province of Sudan. J Trop Med Hyg 97: 228–230. - PubMed
-
- McCarthy MC, Haberberger RL, Salib AW, Soliman BA, el-Tigani A, Khalid IO, Watts DM, 1996. Evaluation of arthropod-borne viruses and other infectious disease pathogens as the causes of febrile illnesses in the Khartoum province of Sudan. J Med Virol 48: 141–146. - PubMed
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