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Randomized Controlled Trial
. 2019:27:e20180442.
doi: 10.1590/1678-7757-2018-0442. Epub 2019 Apr 11.

Effect of dental bleaching on pulp oxygen saturation in maxillary central incisors - a randomized clinical trial

Lima Lorena Ferreira  1 , Alencar Ana Helena Gonçalves de  1 , Daniel de Almeida Decurcio  1 , Julio Almeida Silva  1 , Isabella Negro Favarão  1 , Marco Antônio Zaiden Loureiro  1 , Fernando Branco Barletta  2 , Carlos Estrela  1
Affiliations
Randomized Controlled Trial

Effect of dental bleaching on pulp oxygen saturation in maxillary central incisors - a randomized clinical trial

Lima Lorena Ferreira et al. J Appl Oral Sci. 2019.

Abstract

Objective: To assess pulp oxygen saturation levels (SaO2) in maxillary central incisors after dental bleaching.

Materials and methods: 80 participants (160 teeth) were randomly allocated to four groups: G1 In-office bleaching with two applications of 35% hydrogen peroxide (HP) (20 minutes), followed by at-home bleaching with 10% carbamide peroxide (CP) (2 hours/day for 16 days); G2 - Same protocol as G1, plus desensitizing toothpaste; G3 - In-office bleaching with 35% HP and one application of placebo gel (20 minutes), followed by at-home bleaching with 10% CP (2 hours/day for 16 days); and G4 - Same protocol as G3, plus desensitizing toothpaste. Pulp SaO2 levels were measured before (T0) and immediately after (T1) in-office bleaching; on the 5th (T2), 8th (T3), 12th (T4), and 16th days of at-home bleaching (T5); and on the 7th (T6) and 30th (T7) days. Mean (SD) pulp SaO2 levels were compared within groups by generalized estimating equations (GEE) and Student's t-test (P<0.05).

Results: Mean pulp SaO2 at T0 was 84.29% in G1, 84.38% in G2, 84.79% in G3, and 85.83% in G4. At T1, these values decreased to 81.96%, 82.06%, 82.19%, and 81.15% in G1, G2, G3, and G4 respectively, with significant difference in G4 (P<0.05). During home bleaching, pulp SaO2 levels varied in all groups, with 86.55%, 86.60%, 85.71%, and 87.15% means at T7 for G1, G2, G3, and G4, respectively; G2 presented significant difference (P<0.05).

Conclusions: Pulp SaO2 level in maxillary central incisors was similar at baseline, reducing immediately after in-office bleaching, regardless of using desensitizing toothpaste and increasing at 30 days after dental bleaching.

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Figures

Figure 1
Figure 1. – A) Pulse oximeter and B) sensor with specially manufactured adapter
Figure 2
Figure 2. Flow diagram of study inclusion
Figure 3
Figure 3. Graphical representation of pulp oxygen saturation level (%) at baseline, variations observed during whitening procedures, and levels at the end of the intervention in Group 1 (blue), Group 2 (green), Group 3 (red), and Group 4 (yellow)
See this image and copyright information in PMC

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