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Case Reports
. 2019 Feb 20;7(4):695-698.
doi: 10.1002/ccr3.2072. eCollection 2019 Apr.

A case of palisaded neutrophilic granulomatous dermatitis with subsequent development of chronic myelomonocytic leukemia

Aikaterini Kyriakou  1 , Aikaterini Patsatsi  1 , Vassilios Papadopoulos  2 , Anna Kioumi  2 , Ioannis Efstratiou  3 , Elizabeth Lazaridou  1
Affiliations
Case Reports

A case of palisaded neutrophilic granulomatous dermatitis with subsequent development of chronic myelomonocytic leukemia

Aikaterini Kyriakou et al. Clin Case Rep. .

Abstract

Palisaded neutrophilic granulomatous dermatitis is a cutaneous marker of a systemic disease. Clinicians' goal should be directed toward determining an underlying condition. Even if the initial investigation is inconclusive, it may be necessary that some tests are repeated, since a serious underlying disease could be revealed in the course of time.

Keywords: connective tissue; lymphoproliferative; rheumatoid arthritis; sarcoidosis.

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Conflict of interest statement

None declared.

Figures

Figure 1
Figure 1
Violaceous, indurated plaques located on the head
Figure 2
Figure 2
Initial bone marrow smear showing sparse plasma cells (arrows) and reactive changes—May‐Grunwald‐Giemsa (MGG) stain x 100
Figure 3
Figure 3
Formation of granulomas—H&E X 10
Figure 4
Figure 4
Neutrophilic infiltration and nuclear debris—H&E X 40
Figure 5
Figure 5
A, Peripheral blood on follow‐up suggestive of CMML. B, Bone marrow smear on follow‐up suggestive of CMML. Arrowheads: abnormal monocytes, black arrowheads: blasts, white arrowhead: dysplastic neutrophil, red arrowheads: dysplastic erythroblasts. (MGG x100). B, upper left image (x10) depicts increased cellularity
See this image and copyright information in PMC

References

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