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Editorial
. 2019 Mar;11(Suppl 3):S256-S261.
doi: 10.21037/jtd.2019.01.96.

Spread through air spaces in lung adenocarcinoma: is radiology reliable yet?

Roberta E Ledda  1 , Gianluca Milanese  1 , Letizia Gnetti  2 , Andrea Borghesi  3 , Nicola Sverzellati  1 , Mario Silva  1
Affiliations
Editorial

Spread through air spaces in lung adenocarcinoma: is radiology reliable yet?

Roberta E Ledda et al. J Thorac Dis. 2019 Mar.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Lung adenocarcinoma (dashed line) with multiple areas of STAS (dotted lines). STAS, spread through air spaces.
Figure 2
Figure 2
Morphological heterogeneity of STAS positive lung cancer as displayed by pre-surgical HRCT. (A) Solid nodule with peripheral location and minor subtle spiculations (pT3N0); (B) subsolid mass in the apical segment of left lower lobe (pT1bN0); (C) solid nodule with central hyperlucency on HRCT, defined as cavitation or pseudocavitation (axial reformatting); (D) solid nodule with central hyperlucency on HRCT, defined as cavitation or pseudocavitation (oblique coronal reformatting). STAS, spread through air spaces.
See this image and copyright information in PMC

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References

    1. Travis WD, Brambilla E, Nicholson AG, et al. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol 2015;10:1243-60. 10.1097/JTO.0000000000000630 - DOI - PubMed
    1. Kadota K, Nitadori J, Sima CS, et al. Tumor Spread through Air Spaces is an Important Pattern of Invasion and Impacts the Frequency and Location of Recurrences after Limited Resection for Small Stage I Lung Adenocarcinomas. J Thorac Oncol 2015;10:806-14. 10.1097/JTO.0000000000000486 - DOI - PMC - PubMed
    1. Shiono S, Yanagawa N. Spread through air spaces is a predictive factor of recurrence and a prognostic factor in stage I lung adenocarcinoma. Interact Cardiovasc Thorac Surg 2016;23:567-72. 10.1093/icvts/ivw211 - DOI - PubMed
    1. Toyokawa G, Yamada Y, Tagawa T, et al. Computed tomography features of resected lung adenocarcinomas with spread through air spaces. J Thorac Cardiovasc Surg 2018;156:1670-6.e4. 10.1016/j.jtcvs.2018.04.126 - DOI - PubMed
    1. Kim SK, Kim TJ, Chung MJ, et al. Lung Adenocarcinoma: CT Features Associated with Spread through Air Spaces. Radiology 2018;289:831-40. 10.1148/radiol.2018180431 - DOI - PubMed