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Editorial
. 2019 Mar;11(Suppl 3):S331-S333.
doi: 10.21037/jtd.2018.12.127.

Lymph node metastasis matters

Affiliations
Editorial

Lymph node metastasis matters

Haruhiko Sugimura et al. J Thorac Dis. 2019 Mar.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Tumor infiltrating lymphocytes in metastatic squamous cell carcinoma in the lymph nodes. PD1 expression in lymphocytes is shown. Used antibody is anti PD-1, Clone EH33 (CST Japan, Osaka), with 1:50 dilution and colorized by DAB. 20× objective lens (Keyence BZ-9000).

Comment on

References

    1. Ferrara R, Mezquita L, Texier M, et al. Hyperprogressive Disease in Patients With Advanced Non-Small Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or With Single-Agent Chemotherapy. JAMA Oncol 2018;4:1543-52. 10.1001/jamaoncol.2018.3676 - DOI - PMC - PubMed
    1. Ferrara R, Pilotto S, Caccese M, et al. Do immune checkpoint inhibitors need new studies methodology? J Thorac Dis 2018;10:S1564-S1580. 10.21037/jtd.2018.01.131 - DOI - PMC - PubMed
    1. Seymour L, Bogaerts J, Perrone A, et al. iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics. Lancet Oncol 2017;18:e143-e152. 10.1016/S1470-2045(17)30074-8 - DOI - PMC - PubMed
    1. Champiat S, Dercle L, Ammari S, et al. Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1. Clin Cancer Res 2017;23:1920-8. 10.1158/1078-0432.CCR-16-1741 - DOI - PubMed
    1. Kato S, Goodman A, Walavalkar V, et al. Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate. Clin Cancer Res 2017;23:4242-50. 10.1158/1078-0432.CCR-16-3133 - DOI - PMC - PubMed