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. 1986 Dec 15;141(2):790-6.
doi: 10.1016/s0006-291x(86)80242-x.

Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease

E Montejo de Garcini, L Serrano, J Avila

Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease

E Montejo de Garcini et al. Biochem Biophys Res Commun. .

Abstract

Microtubule associated protein tau factor self-assembles into filamentous structures resembling the paired helical filaments found in Alzheimer disease. Tau polymerization requires of a previous modification; conversion of glutamine into glutamic acid by deamination.

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