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Comparative Study
. 1986 Sep;6(3):325-9.
doi: 10.1007/BF00711117.

Dopamine- and octopamine-sensitive adenylate cyclase in the brain of adult Culex pipiens mosquitoes

S Pratt, S C Pryor
Comparative Study

Dopamine- and octopamine-sensitive adenylate cyclase in the brain of adult Culex pipiens mosquitoes

S Pratt et al. Cell Mol Neurobiol. 1986 Sep.

Abstract

The effects of dopamine and octopamine on adenylate cyclase activity were studied on the head homogenate of adult Culex pipiens mosquitoes in vitro. Both dopamine and octopamine were shown to increase the cyclic AMP content in the homogenate. The antagonist haloperidol blocked the production of cyclic AMP induced from dopamine but had no effect on the production of cyclic AMP induced by octopamine at the concentrations tested. The opiate agonist etorphine was ineffective at reducing cyclic AMP levels induced by either dopamine or octopamine at the concentrations tested.

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