Lethal clues to cancer-cell vulnerability
- PMID: 31000834
- DOI: 10.1038/d41586-019-01086-w
Lethal clues to cancer-cell vulnerability
Keywords: Cancer; Medical research.
Comment on
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Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells.Elife. 2019 Mar 25;8:e43333. doi: 10.7554/eLife.43333. Elife. 2019. PMID: 30910006 Free PMC article.
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WRN helicase is a synthetic lethal target in microsatellite unstable cancers.Nature. 2019 Apr;568(7753):551-556. doi: 10.1038/s41586-019-1102-x. Epub 2019 Apr 10. Nature. 2019. PMID: 30971823 Free PMC article.
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Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.Nature. 2019 Apr;568(7753):511-516. doi: 10.1038/s41586-019-1103-9. Epub 2019 Apr 10. Nature. 2019. PMID: 30971826
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