Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jul;29(7):2110-2114.
doi: 10.1007/s11695-019-03760-4.

Incidence and Risk Factors for Cholelithiasis After Bariatric Surgery

Affiliations

Incidence and Risk Factors for Cholelithiasis After Bariatric Surgery

Hernán M Guzmán et al. Obes Surg. 2019 Jul.

Erratum in

Abstract

Background: Obesity and rapid weight loss after bariatric surgery (BS) are independent risk factors for development of cholelithiasis (CL), a prevalent disease in the Chilean population. This study aimed to determine the incidence of CL in obese Chilean patients 12 months after BS and identify risk factors for development of gallstones.

Methods: Retrospective study of patients who underwent BS in 2014. Patients with preoperative negative abdominal ultrasound (US) for CL and follow-up for at least than 12 months were included. Patients underwent US at 6 months and 12 months. We analyzed sex, age, hypertension, dyslipidemia, type 2 diabetes mellitus, body mass index (BMI), surgical procedure, percentage of excess BMI loss (%EBMIL) at 6 months, and BMI at 6 months.

Results: Of 279 patients who underwent bariatric surgery during 2014, 66 had previous gallbladder disease and 176 met the inclusion criteria (82.6%), while 54.6% were female. The mean age was 37.8 ± 10.5 years and preoperative BMI was 37.5 kg/m2. BMI and %EBMIL at 6 months were 27.8 ± 3.3 kg/m2 and 77.9 ± 33.6%, respectively. At 12 months after BS, CL was found in 65 patients (36.9%). Hypertension turned out to be protective against occurrence of gallstones at 1 year with an OR 0.241.

Conclusions: Incidence of CL was up to one-third of the patients followed up for 12 months after BS. Excessive weight loss and other variables studied did not increase risk. Hypertension seems to be protective against gallstone formation, but this result needs further analysis.

Keywords: Bariatric surgery; Cholelithiasis; Obesity; Roux-en-Y gastric bypass; Sleeve gastrectomy; Sleeve gastrectomy with jejunal bypass; Weight loss.

PubMed Disclaimer

References

    1. Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017;27(9):2279–89. https://doi.org/10.1007/s11695-017-2666-x . - DOI - PubMed - PMC
    1. Covarrubias C, Valdivieso V, Nervi F. Epidemiology of gallstone disease in Chile. In: Capocaccia L, Ricci G, Angelico F, Angelico M, Attili AF, editors. Epidemiology and prevention of gallstone disease. Dordrecht: Springer; 1984.
    1. Amaral J, Thompson W. Gallbladder disease in the morbidly obese. Am J Surg. 1985;149(4):551–7. - DOI - PubMed
    1. Warschkow R, Tarantino I, Ukegjini K, et al. Concomitant cholecystectomy during laparoscopic Roux-en-Y gastric bypass in obese patients is not justified: a meta-analysis. Obes Surg. 2013;23(3):397–407. https://doi.org/10.1007/s11695-012-0852-4 . - DOI - PubMed
    1. Shiffman ML, Sugerman HJ, Kellum JM, et al. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol. 1991;86:1000–5. - PubMed

MeSH terms

LinkOut - more resources