Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Abstract

We detected Zika virus RNA in rectal swab samples from 10 patients by using real-time reverse transcription PCR, and we isolated the virus from 1 patient. The longest interval from symptom onset to detection was 14 days. These findings are applicable to diagnosis and infection prevention recommendations.

Keywords: Brazil; Zika virus; infection; rectal swab; sexual transmission; virus persistence; viruses.

PubMed Disclaimer

Figures

Figure
Figure
Detection of Zika virus RNA in human biological specimens from 8 patients, according to Ct and days after disease onset. Patient identification numbers above charts correspond to numbers in the Table. Horizontal dashed lines indicate real-time reverse transcription PCR cutoff Ct of 38. Disease onset is day 0 (screening visit), defined after interviewing patients about symptoms. Ct, cycle threshold.

References

    1. Faria NR, Azevedo RDSDS, Kraemer MUG, Souza R, Cunha MS, Hill SC, et al. Zika virus in the Americas: Early epidemiological and genetic findings. Science. 2016;352:345–9. 10.1126/science.aaf5036 - DOI - PMC - PubMed
    1. Miranda-Filho DB, Martelli CMT, Ximenes RA, Araújo TV, Rocha MA, Ramos RC, et al. Initial description of the presumed congenital Zika syndrome. Am J Public Health. 2016;106:598–600. 10.2105/AJPH.2016.303115 - DOI - PMC - PubMed
    1. Paz-Bailey G, Rosenberg ES, Doyle K, Munoz-Jordan J, Santiago GA, Klein L, et al. Persistence of Zika virus in body fluids–preliminary report. N Engl J Med. 2017;379:1234–43. 10.1056/NEJMoa1613108 - DOI - PMC - PubMed
    1. Barzon L, Percivalle E, Pacenti M, Rovida F, Zavattoni M, Del Bravo P, et al. Virus and antibody dynamics in travelers with acute Zika virus infection. Clin Infect Dis. 2018;66:1173–80. 10.1093/cid/cix967 - DOI - PubMed
    1. Li C, Deng Y-Q, Zu S, Quanquin N, Shang J, Tian M, et al. Zika virus shedding in the stool and infection through the anorectal mucosa in mice. Emerg Microbes Infect. 2018;7:169. 10.1038/s41426-018-0170-6 - DOI - PMC - PubMed

Publication types