Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jul:36:32-39.
doi: 10.1016/j.blre.2019.04.002. Epub 2019 Apr 13.

Extramedullary disease in multiple myeloma - controversies and future directions

Sabina Sevcikova  1 , Jiri Minarik  2 , Martin Stork  3 , Tomas Jelinek  4 , Ludek Pour  5 , Roman Hajek  6
Affiliations
Free article
Review

Extramedullary disease in multiple myeloma - controversies and future directions

Sabina Sevcikova et al. Blood Rev. 2019 Jul.
Free article

Abstract

Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.

Keywords: Biomarker; Extramedullary disease; Multiple myeloma; Resistance; Treatment.

PubMed Disclaimer

Publication types

LinkOut - more resources