Knowledge of patients on safe medication use in relation to nonsteroidal anti-inflammatory drugs
- PMID: 31007655
- PMCID: PMC6448436
- DOI: 10.4103/sja.SJA_557_18
Knowledge of patients on safe medication use in relation to nonsteroidal anti-inflammatory drugs
Abstract
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed and used medications that are used as analgesic, antipyretic, or anti-inflammatory agents, but have a high risk of adverse effects.
Objective: The main purpose of this study is to evaluate the knowledge of patients toward the risks and safe usage of NSAIDs.
Methods: A descriptive cross-sectional study was conducted among patients who attended orthopedic clinics at King Khalid University Hospital in Riyadh, Saudi Arabia, during December 2017 to February 2018. A self-administered questionnaire comprising three sections [sociodemographic information, patients' knowledge of NSAIDs, and the attitude toward receiving information about NSAIDs' adverse drug reactions (ADRs)] was used. The attitude was measured with a 5-point Likert scale.
Results: The mean duration of NSAIDs usage was 7.3 ± 6.9 years. Only 45% of the respondents used NSAIDs daily, while 38% said they only used NSAIDs as needed. Nearly one-quarter of patients (25.5%) were counseled by a healthcare provider on the risks of NSAIDs. Almost 94% and 90.5% of the study subjects agreed that physicians and pharmacists, respectively, should play an essential role in providing information regarding ADRs to their patients. More than half of the respondents claimed that information about ADRs might lead them to discontinue their medicines. More than one-third of respondents stated that their healthcare setting provided them with insufficient knowledge of ADRs.
Conclusion: Counseling of patients may diminish potentially inappropriate use and increase risk awareness. Healthcare providers can improve their role in identifying and counseling patients on NSAIDs.
Keywords: Adverse drug reactions; Saudi Arabia; attitude; counseling; knowledge; nonsteroidal anti-inflammatory drugs.
Conflict of interest statement
There are no conflicts of interest.
Similar articles
-
Knowledge About and the Use of Oral Nonsteroidal Anti-inflammatory Drugs Among Patients With Rheumatic Disorders in Saudi Arabia: A Cross-Sectional Study.Cureus. 2023 Nov 8;15(11):e48500. doi: 10.7759/cureus.48500. eCollection 2023 Nov. Cureus. 2023. PMID: 38073919 Free PMC article.
-
Medication safety knowledge, attitude, and practice among hospital pharmacists in tertiary care hospitals in Saudi Arabia: a multi-center study.Arch Public Health. 2021 Jul 12;79(1):130. doi: 10.1186/s13690-021-00616-1. Arch Public Health. 2021. PMID: 34253257 Free PMC article.
-
Knowledge and Attitude of Iraqi Pharmacists Regarding the Adverse Effects of NSAIDs Based on Years of Experience.Turk J Pharm Sci. 2025 Mar 7;22(1):26-37. doi: 10.4274/tjps.galenos.2024.92185. Turk J Pharm Sci. 2025. PMID: 40052361 Free PMC article.
-
Adverse drug reactions and drug-drug interactions with over-the-counter NSAIDs.Ther Clin Risk Manag. 2015 Jul 15;11:1061-75. doi: 10.2147/TCRM.S79135. eCollection 2015. Ther Clin Risk Manag. 2015. PMID: 26203254 Free PMC article. Review.
-
Why Pharmacovigilance of Non-steroidal Anti-inflammatory Drugs is Important in India?Endocr Metab Immune Disord Drug Targets. 2024;24(7):731-748. doi: 10.2174/0118715303247469230926092404. Endocr Metab Immune Disord Drug Targets. 2024. PMID: 37855282 Review.
Cited by
-
Evaluation of the England Community Pharmacy Quality Scheme (2018-2019 and 2019-2020) in reducing harm from NSAIDs in older patients.BMJ Open Qual. 2023 Jan;12(1):e002002. doi: 10.1136/bmjoq-2022-002002. BMJ Open Qual. 2023. PMID: 36593072 Free PMC article.
-
Prevalence, awareness, and patterns of non-steroidal anti-inflammatory drug use among health science students in Palestine: a cross-sectional study.Sci Rep. 2023 Nov 13;13(1):19844. doi: 10.1038/s41598-023-47279-2. Sci Rep. 2023. PMID: 37963981 Free PMC article.
-
Knowledge, Attitude and Practice Regarding Nonsteroidal Anti-inflammatory Drugs and Corticosteroids Use Among Patients With Chronic Rheumatology Condition: A Cross-Sectional Study From Vietnam.Clin Med Insights Arthritis Musculoskelet Disord. 2024 Dec 23;17:11795441241308876. doi: 10.1177/11795441241308876. eCollection 2024. Clin Med Insights Arthritis Musculoskelet Disord. 2024. PMID: 39717067 Free PMC article.
-
Ambulatory Heart Function and Transplant Patients' Perceptions of Drug-Drug Interactions: A Qualitative Study.Can J Hosp Pharm. 2022 Spring;75(2):71-78. doi: 10.4212/cjhp.v75i2.3074. Epub 2022 Apr 4. Can J Hosp Pharm. 2022. PMID: 35387374 Free PMC article.
-
Characterization of potentially inappropriate medication prescriptions for the elderly in primary care and hospital settings.J Family Med Prim Care. 2021 Aug;10(8):3111-3115. doi: 10.4103/jfmpc.jfmpc_271_21. Epub 2021 Aug 27. J Family Med Prim Care. 2021. PMID: 34660455 Free PMC article.
References
-
- Gotzsche PC. Methodology and overt hidden bias in reports of 196 double-blind trials of non-steroidal anti-inflammatory drugs in rheumatoid arthritis. Control Clin Trials. 1989;10:31–56. - PubMed
-
- Van Tulder MW, Scholten R, Koes BW, Deyo RA. Non-steroidal anti-inflammatory drugs for low-back pain. Cochrane Database Syst Rev. 2006;1:CD000396. - PubMed
-
- Jani UA, Ford ES, Greenland KJ, Giles WH, Mokdad AH. Aspirin use among U.S. adults: Behavioral Risk Factor Surveillance System. Am J Prev Med. 2006;30:74–7. - PubMed