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Review
. 2019 Apr 10:7:2050312119843700.
doi: 10.1177/2050312119843700. eCollection 2019.

Hypertension in pregnancy: Pathophysiology and treatment

Stephanie Braunthal  1 , Andrei Brateanu  1
Affiliations
Review

Hypertension in pregnancy: Pathophysiology and treatment

Stephanie Braunthal et al. SAGE Open Med. .

Abstract

Hypertensive disorders of pregnancy, an umbrella term that includes preexisting and gestational hypertension, preeclampsia, and eclampsia, complicate up to 10% of pregnancies and represent a significant cause of maternal and perinatal morbidity and mortality. Despite the differences in guidelines, there appears to be consensus that severe hypertension and non-severe hypertension with evidence of end-organ damage need to be controlled; yet the ideal target ranges below 160/110 mmHg remain a source of debate. This review outlines the definition, pathophysiology, goals of therapy, and treatment agents used in hypertensive disorders of pregnancy.

Keywords: Hypertension; gestational hypertension; pregnancy.

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Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Bateman BT, Shaw KM, Kuklina EV, et al. Hypertension in women of reproductive age in the United States: NHANES 1999–2008. PLoS ONE 2012; 7(4): e36171. - PMC - PubMed
    1. American College of Obstetricians and Gynecologists; Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol 2013; 122: 1122–1131. - PubMed
    1. ACOG practice bulletin no. 202: gestational hypertension and preeclampsia. Obstet Gynecol 2019; 133: e1–e25. - PubMed
    1. Butalia S, Audibert F, Cote AM, et al. Hypertension Canada’s 2018 guidelines for the management of hypertension in pregnancy. Can J Cardiol 2018; 34(5): 526–531. - PubMed
    1. Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, et al. 2018 ESC guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J 2018; 39: 3165–3241. - PubMed

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