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Review
. 2019 Mar 17:2019:8217602.
doi: 10.1155/2019/8217602. eCollection 2019.

Oral Applications of Cyanoacrylate Adhesives: A Literature Review

Eduardo Borie  1 , Eduardo Rosas  1 , Gisaku Kuramochi  2 , Sophia Etcheberry  3 , Sergio Olate  4 , Benjamin Weber  1
Affiliations
Review

Oral Applications of Cyanoacrylate Adhesives: A Literature Review

Eduardo Borie et al. Biomed Res Int. .

Abstract

Cyanoacrylate adhesives have been used in medicine and dentistry with some controversial opinions. The aim of this review was to summarize the relevant literature regarding the use of cyanoacrylate adhesives for oral wounds during dental and surgical procedures, with focus on the applications, indications, advantages, and disadvantages. In conclusion, in vivo and clinical studies have demonstrated in the last few years convincing results regarding the safety, efficacy, ease of application, and feasibility of all types of cyanoacrylate adhesives used in intra- and extraoral procedures.

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Figures

Figure 1
Figure 1
Wound closure in a moist environment during an apical surgery with an adhesive composed of n-butyl-cyanoacrylate and octyl cyanoacrylate.
Figure 2
Figure 2
Application of ethyl cyanoacrylate adhesive during a dental implant placement procedure to achieve immediate hemostasis in a patient that uses anticoagulant therapy.
See this image and copyright information in PMC

References

    1. Montanaro L., Arciola C. R., Cenni E., et al. Cytotoxicity, blood compatibility and antimicrobial activity of two cyanoacrylate glues for surgical use. Biomaterials. 2001;22(1):59–66. doi: 10.1016/S0142-9612(00)00163-0. - DOI - PubMed
    1. Kumar M. S., Natta S., Shankar G., Reddy S. H., Visalakshi D., Seshiah G. V. Comparison between silk sutures and cyanoacrylate adhesive in human mucosa- a clinical and histological study. Journal of International Oral Health. 2013;5:95–100. - PMC - PubMed
    1. Moretti Neto R. T., Mello I., Moretti A. B. D. S., Robazza C. R. C., Pereira A. A. C. In vivo qualitative analysis of the biocompatibility of different cyanoacrylate-based adhesives. Brazilian Oral Research. 2008;22(1):43–47. doi: 10.1590/S1806-83242008000100008. - DOI - PubMed
    1. Soni A., Narula R., Kumar A., Parmar M., Sahore M., Chandel M. Comparing cyanoacrylate tissue adhesive and conventional subcuticular skin sutures for maxillofacial incisions—a prospective randomized trial considering closure time, wound morbidity, and cosmetic outcome. Journal of Oral and Maxillofacial Surgery. 2013;71(12):2152.e1–2152.e8. doi: 10.1016/j.joms.2013.08.029. - DOI - PubMed
    1. Sagar P., Prasad K., Lalitha R. M., Ranganath K. Cyanoacrylate for intraoral wound closure: a possibility? International Journal of Biomaterials. 2015;2015:6. doi: 10.1155/2015/165428.165428 - DOI - PMC - PubMed

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