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Case Reports
. 2019 Apr 5;5(4):372-374.
doi: 10.1016/j.jdcr.2019.02.021. eCollection 2019 Apr.

Rosai-Dorfman disease simulating metastatic breast carcinoma

Kenneth K Yu  1 , Naomi F Briones  2 , May Chan  3   4 , Asra Ahmed  5 , Erica Stevens  4
Affiliations
Case Reports

Rosai-Dorfman disease simulating metastatic breast carcinoma

Kenneth K Yu et al. JAAD Case Rep. .
No abstract available

Keywords: Rosai–Dorfman disease; metastatic breast cancer; monoclonal gammopathy.

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Figures

Fig 1
Fig 1
Rosai–Dorfman disease. Left upper arm with multiple keloidal pink smooth papules in a clustered configuration overlying a 4- to 5-cm dermal/subcutaneous firm tethered nodule.
Fig 2
Fig 2
Rosai–Dorfman disease. Telescoping punch biopsy specimen obtained from a nodule on the left upper arm. Both the superficial papule and the deeper subcutaneous nodule (A) consist of a dense infiltrate of large pale histiocytes admixed with lymphocytes, plasma cells, and neutrophils. Some of the histiocytes contain intact inflammatory cells (predominantly neutrophils) within the cytoplasm, a process known as “emperipolesis” (B). These histiocytes are highlighted by S100 immunostain (C). (Original magnification: A and B, ×40; C and D, ×400.)
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