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Case Reports
. 2019 Apr 6;5(4):389-391.
doi: 10.1016/j.jdcr.2019.02.010. eCollection 2019 Apr.

Touch preparation of skin biopsy specimen for rapid diagnosis of cutaneous Nocardia nova in the immunocompromised host

Edward C Traver  1   2 , Sameera Husain  3 , Marc E Grossman  4   5
Affiliations
Case Reports

Touch preparation of skin biopsy specimen for rapid diagnosis of cutaneous Nocardia nova in the immunocompromised host

Edward C Traver et al. JAAD Case Rep. .
No abstract available

Keywords: AFB, acid-fast bacilli; GMS, Gomori methenamine silver; Nocardia nova; immunocompromised; touch preparation.

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Figures

Fig 1
Fig 1
Red-brown papulonodules were present on the anterior surface of the right lower leg of a transplant patient for 2 days and diagnosed as cutaneous Nocardia nova. Inset, Wider view of the same leg.
Fig 2
Fig 2
Touch preparation of a punch biopsy specimen of right lower leg papulonodules, prepared with modified acid-fast stain, revealed abundant acid-fast branching filaments in a background of neutrophils consistent with Nocardia. (Original magnification: ×40.)
Fig 3
Fig 3
Gomori methenamine silver staining of a biopsy specimen obtained from right lower leg nodules revealed branching filamentous organisms consistent with Nocardia. (Original magnification: ×100.)
Fig 4
Fig 4
Fungal culture of the skin biopsy specimen revealed white cotton ball–like colonies on chocolate agar after 2 weeks of incubation, identified as Nocardia nova.
See this image and copyright information in PMC

References

    1. Kalb R.E., Kaplan M.H., Grossman M.E. Cutaneous nocardiosis. Case reports and review. J Am Acad Dermatol. 1985;13:125–133. - PubMed
    1. Shapiro P.E., Grossman M.E. Disseminated Nocardia asteroides with pustules. J Am Acad Dermatol. 1989;20:889–892. - PubMed
    1. Grossman M.E., Fox L.P., Kovarik C., Rosenbach M. Springer-Verlag; New York: 2012. Cutaneous manifestations of infection in the immunocompromised host.
    1. Lebeaux D., Morelon E., Suarez F. Nocardiosis in transplant recipients. Eur J Clin Microbiol Infect Dis. 2014;33:689–702. - PubMed
    1. Shannon K., Pasikhova Y., Ibekweh Q., Ludlow S., Baluch A. Nocardiosis following hematopoietic stem cell transplantation. Transpl Infect Dis. 2016;18:169–175. - PubMed

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