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Comment
. 2018 Jul 9;5(4):ENEURO.0255-18.2018.
doi: 10.1523/ENEURO.0255-18.2018. eCollection 2018 Jul-Aug.

Identification of a Novel Molecular Target for Alcohol Dependence

Rosalind S E Carney
Comment

Identification of a Novel Molecular Target for Alcohol Dependence

Rosalind S E Carney. eNeuro. .
No abstract available

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Figures

Figure 1.
Figure 1.
GPR139 agonist JNJ-63533054 reduces alcohol dependence and increases the pain threshold. Intra-habenular infusion of JNJ-63533054 decreased alcohol self-administration in alcohol-dependent rats compared to vehicle-treated rats. No effect on water intake was observed. During alcohol withdrawal, intra-habenular infusion of JNJ-63533054 increased paw withdrawal thresholds compared to vehicle-treated rats. (Figure courtesy of Jenni Kononoff.)
See this image and copyright information in PMC

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