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Review
. 2019 Apr 20;7(2):33.
doi: 10.3390/biomedicines7020033.

Oral and Psychological Alterations in Haemophiliac Patients

Luca Fiorillo  1   2 , Rosa De Stefano  3 , Gabriele Cervino  4 , Salvatore Crimi  5 , Alberto Bianchi  6 , Paola Campagna  7 , Alan Scott Herford  8 , Luigi Laino  9 , Marco Cicciù  10
Affiliations
Review

Oral and Psychological Alterations in Haemophiliac Patients

Luca Fiorillo et al. Biomedicines. .

Abstract

Haemophiliacs are hereditary coagulopathies whose basic anomaly consists of the quantitative or qualitative alteration of one or more plasma proteins in the coagulation system. The objective of this review is to analyse all risk factors, predispositions and alterations to the oral-maxillofacial district in patients with haemophilia. The broader assessment also includes the psychological aspects that could affect the treatment and maintenance of oral conditions. The study takes into consideration all the works in the literature in the last 10 years. Works that present oral, dental and psychological changes in haemophilia patients have been combined. A total of 16 studies were analysed carefully evaluating and explaining all the alterations and risk factors that this disease provides. The aim of the review is to report all the anomalies reported in the literature for these patients, and to direct and update the clinician in the treatment of haemophilia patients.

Keywords: dental risk factor; haemophilia; oral alterations; psychological conditions.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram.
See this image and copyright information in PMC

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