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Review
. 2019 Apr 19;7(2):32.
doi: 10.3390/biomedicines7020032.

Women's Health: Contemporary Management of MS in Pregnancy and Post-Partum

Kelly Tisovic  1 , Lilyana Amezcua  2
Affiliations
Review

Women's Health: Contemporary Management of MS in Pregnancy and Post-Partum

Kelly Tisovic et al. Biomedicines. .

Abstract

Multiple sclerosis (MS) primarily affects women in childbearing age and is associated with an increased risk of adverse post-partum outcomes. Relapses and now fetal exposure to disease modifying treatments in the early phase of pregnancy and thereafter are of concern. Safe and effective contraception is required for women who wish to delay or avoid pregnancy while on disease-modifying treatments. Counseling and planning is essential to assess the risk of both fetal and maternal complications, particularly now in the era of highly efficient and riskier therapies. The purpose of this review is to provide a practical framework using the available data surrounding pregnancy in MS with the goal of optimizing outcomes during this phase in MS.

Keywords: multiple sclerosis; post-partum; pregnancy; treatment.

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Conflict of interest statement

Amezcua has received personal compensation for consulting, serving on a scientific advisory board, or other activities with Genzyme and Serono. She has clinical trial research funding from Medday.

Figures

Figure 1
Figure 1
Pre-pregnancy care. (A) Multiple sclerosis (MS) disease activity assessment, (B) medication reconciliation, (C) anticipation of issues during pregnancy and post-partum.
See this image and copyright information in PMC

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