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. 2019:41:e2019016.
doi: 10.4178/epih.e2019016. Epub 2019 Apr 23.

Risk factors contributing to the incidence and mortality of acute childhood poisoning in emergency department patients in Iran: a hospital-based casecontrol study

Hamideh Feiz Disfani  1 , Mostafa Kamandi  2 , Seyed Mohammad Mousavi  1 , Sayyed Majid Sadrzadeh  1 , Roohie Farzaneh  1 , Najme Doolabi  1 , Kazem Rahmani  3
Affiliations

Risk factors contributing to the incidence and mortality of acute childhood poisoning in emergency department patients in Iran: a hospital-based casecontrol study

Hamideh Feiz Disfani et al. Epidemiol Health. 2019.

Abstract

Objectives: Since poisoning is one of the most important preventable factors contributing to the hospitalization and death of children who present to emergency departments, this study was carried out to investigate the risk factors contributing to the incidence and mortality of acute childhood poisoning.

Methods: This hospital-based case-control study included 243 cases and 489 controls, drawn from daily admissions to the emergency departments of the included hospitals according to the inclusion and exclusion criteria.

Results: Gastrointestinal poisoning was the most common poisoning type, found in 87.7% of subjects, and medications were the most common cause of poisoning (49.8%). Multiple logistic regression analysis showed that a history of poisoning (odds ratio [OR], 10.44; 95% confidence interval [CI], 5.58 to 19.51; p<0.001) and the availability of poisonous substances (OR, 8.88; 95% CI, 5.41 to 14.56; p<0.001) were among the most important predictors of childhood poisoning. Respiratory poisoning (OR, 6.72; 95% CI, 1.40 to 32.07; p<0.05) and the presence of addiction in the family (OR, 4.54; 95% CI, 1.10 to 18.68; p<0.05) were the most important predictors of mortality among children with poisoning.

Conclusions: Addiction and the presence of physical or psychological disorders in family members, a history of poisoning, and the availability of poisonous substances were significantly associated with the incidence of childhood poisoning and resultant mortality.

Keywords: Child; Emergency department; Iran; Mortality; Poisoning.

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Conflict of interest statement

The authors have no conflicts of interest to declare for this study.

Figures

Figure 1.
Figure 1.
Evaluation of the multiple logistic regression model through the area under the receiver operating characteristic (ROC) curve.
See this image and copyright information in PMC

References

    1. Bronstein AC, Spyker DA, Cantilena LR, Jr, Green JL, Rumack BH, Heard SE, et al. 2007 Annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 25th annual report. Clin Toxicol (Phila) 2008;46:927–1057. - PubMed
    1. Kissoon N, Argent A, Devictor D, Madden MA, Singhi S, van der Voort E, et al. World Federation of Pediatric Intensive and Critical Care Societies—Its global agenda. Pediatr Crit Care Med. 2009;10:597–600. - PubMed
    1. Pawłowicz U, Wasilewska A, Olański W, Stefanowicz M. Epidemiological study of acute poisoning in children: a 5-year retrospective study in the Paediatric University Hospital in Bialystok, Poland. Emerg Med J. 2013;30:712–716. - PubMed
    1. Antonogeorgos G, Panagiotakos DB, Priftis KN, Tzonou A. Logistic regression and linear discriminant analyses in evaluating factors associated with asthma prevalence among 10-to 12-years-old children: divergence and similarity of the two statistical methods. Int J Pediatr. 2009;2009:952042. - PMC - PubMed
    1. Oguche S, Bukbuk DN, Watila IM. Pattern of hospital admissions of children with poisoning in the Sudano-Sahelian North eastern Nigeria. Niger J Clin Pract. 2007;10:111–115. - PubMed