Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 May 1;24(3):e281-e289.
doi: 10.4317/medoral.22670.

Oral health related quality of life and determinant factors in patients with head and neck cancer

Affiliations

Oral health related quality of life and determinant factors in patients with head and neck cancer

N-B de Melo et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Background: The present study aimed to measure the impact of oral health on the quality of life of patients with head and neck cancer.

Material and methods: A cross-sectional study was conducted with 130 patients diagnosed with head and neck cancer at two medical centers. Participants answered a sociodemographic questionnaire and the Oral Health Impact Profile - 14 (OHIP-14). Clinical aspects, cancer staging, and treatment approach were also investigated. Mann-Whitney and Kruskal-Wallis non-parametric tests were used for statistical analysis, followed by Poisson regression analysis (with robust error variance), to associate the OHIP-14 scores with independent variables.

Results: The OHIP-14 presented good internal consistency (Cronbach's Alpha = 0.861). The mean score obtained was 19.52 (±11.79). Physical pain (3.70±2.44), physical disability (3.26±2.62) and functional limitation (3.24±2.45) were ranked as the main factors affecting the quality of life. Patients non-Caucasians (PR = 1.30; IC 95% = 1.07-1.58; p = 0.009), widowers (PR = 1.36; IC 95% = 1.13-1.64; p = 0.001), diagnosed with squamous cell carcinoma (PR = 1.28; IC 95% = 1.05-1.58; p = 0.017) and with temporomandibular pain (PR = 1.31; IC 95% = 1.08-1.60; p = 0.007) were more likely to exhibit lower rates of quality of life.

Conclusions: The results showed a high impact of the oral health in the quality of life of patients with head and neck cancer was observed. Sociodemographic and clinical characteristics can exert influence on the quality of life of patients with head and neck cancer.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement:The authors have declared that no conflict of interest exist.

References

    1. Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C. Cancer Incidence and Mortality Worldwide: IARC Cancer Base. Lyon: GLOBOCAN; 2013. - PubMed
    1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics 2012. CA Cancer J Clin. 2015;65:87–108. - PubMed
    1. LeHew CW, Weatherspoon DJ, Peterson CE, Goben A, Reitmajer K, Sroussi H. The health system and policy implications of changing epidemiology for oral cavity and oropharyngeal cancers in the United States from 1995 to 2016. Epidemiologic Reviews. 2017;39:132–47. - PubMed
    1. Dhanuthai K, Rojanawatsirivej S, Thosaporn W, Kintarak S, Subarnbhesaj A, Darling M. Oral cancer: A multicenter study. Med Oral Patol Oral Cir Bucal. 2018;23:23–9. - PMC - PubMed
    1. Shavi GR, Thakur B, Bhambal A, Jain S, Singh V, Shukla A. Oral health related quality of life in patients of head and neck cancer attending cancer Hospital of Bhopal City, India. J Int Oral Health. 2015;7:21–7. - PMC - PubMed