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Case Reports
. 2019 Apr 3:22:e00111.
doi: 10.1016/j.crwh.2019.e00111. eCollection 2019 Apr.

Hyperprolactinemia associated with macroprolactinoma in a 17-year-old: A case report

Adam Czyzyk  1 , Rafal Kurzawa  1   2
Affiliations
Case Reports

Hyperprolactinemia associated with macroprolactinoma in a 17-year-old: A case report

Adam Czyzyk et al. Case Rep Womens Health. .

Abstract

Hyperprolactinemia is a relatively common endocrine disorder. In women of reproductive age it may present as the amenorrhea-galactorrhea syndrome, but in milder forms also as menstrual abnormalities or infertility. Here we describe a 17-year-old girl previously treated with a combined oral contraceptive due to secondary amenorrhea. Hormonal tests showed hypogonadotropic hypogonadism with severe hyperprolactinemia (PRL concentration 1639 ng/ml). Further tests confirmed the presence of a pituitary macroadenoma. Cabergoline treatment was effective in the restoration of a spontaneous menstrual cycle and PRL normalization. In conclusion, clinicians should be aware of the diagnostic and therapeutic problems in the management of hyperprolactinemia.

Keywords: Hyperprolactinemia; PRL; Prolactinoma; Secondary amenorrhea.

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Figures

Fig. 1
Fig. 1
MRI scan of the pituitary gland in the sagittal plane at the time of diagnosis (A) and after 12 months of cabergoline therapy (B).
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