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Case Reports
. 2019 Nov;181(5):1068-1070.
doi: 10.1111/bjd.18031. Epub 2019 Jul 18.

Development of inflammatory arthritis and enthesitis in patients on dupilumab: a case series

Z N Willsmore  1 , R T Woolf  1 , C Hughes  2 , B Menon  2 , B Kirkham  2 , C H Smith  1 , A E Pink  1
Affiliations
Case Reports

Development of inflammatory arthritis and enthesitis in patients on dupilumab: a case series

Z N Willsmore et al. Br J Dermatol. 2019 Nov.
No abstract available

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References

    1. Simpson EL, Bieber T, Guttman-Yassky E et al. Two phase 3 trials of dupilumab versus placebo in atopic dermatitis. N Engl J Med 2016; 375:2335-48.
    1. Blauvelt A, de Bruin-Weller M, Gooderham M et al. Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial. Lancet 2017; 389:2287-303.
    1. Summary of Product Characteristics (SmPC). Dupixent. Available at: https://www.medicines.org.uk/emc/product/8553 (last accessed 19 February 2019).
    1. Ou Z, Chen C, Chen A et al. Adverse events of dupilumab in adults with moderate-to-severe atopic. Int Immunopharmacol 2018; 54:303-10.
    1. Joosten LA, Lubberts E, Durez P et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 1997; 40:249-60.

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