Isolated Starvation Ketoacidosis: A Rare Cause of Severe Metabolic Acidosis Presenting with a pH Less than 7
- PMID: 31019864
- PMCID: PMC6467431
- DOI: 10.7759/cureus.4086
Isolated Starvation Ketoacidosis: A Rare Cause of Severe Metabolic Acidosis Presenting with a pH Less than 7
Abstract
Anion gap metabolic acidosis (AGMA) occurs when an anion gap exists along with metabolic acidosis, most commonly due to diabetic ketoacidosis (DKA) and lactic acidosis (LA). Isolated starvation ketoacidosis (ISK) is one of the rare causes of AGMA; however, it usually presents with a mild disturbance in pH. We report a rare case of a 45-year-old female with previously diagnosed squamous cell cancer (SCC) of the larynx. She presented to the emergency department complaining of difficulty in breathing following laryngectomy and tracheostomy for SCC. Her laboratory results on admission were consistent for isolated starvation ketoacidosis and the patient responded quickly to the appropriate treatment.
Keywords: agma; anion gap metabolic acidosis; isk; ketoacidosis; ketosis; metabolic acidosis; ph; starvation.
Conflict of interest statement
The authors have declared that no competing interests exist.
References
-
- Metabolic acidosis in the intensive care unit. [Feb;2019 ];Gauthier PM, Szerlip HM. https://www.ncbi.nlm.nih.gov/pubmed/12053835. Crit Care Clin. 2002 18:289–308. - PubMed
-
- Acid-base aspects of ketoacidosis. Oster JR, Epstein M. Am J Nephrol. 1984;4:137–151. - PubMed
-
- Starvation ketoacidosis in pregnancy. Frise CJ, Mackillop L, Joash K, Williamson C. Eur J Obstet Gynecol Reprod Biol. 2013;167:1–7. - PubMed
-
- Acute starvation in pregnancy: a cause of severe metabolic acidosis. Patel A, Felstead D, Doraiswami M, Stocks GM, Waheed U. Int J Obstet Anesth. 2011;20:253–256. - PubMed
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