Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

doi:10.21037/atm.2019.01.09

Editorial

. 2019 Mar;7(5):83.

doi: 10.21037/atm.2019.01.09.

Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

Jens Juul Holst¹

Affiliations

PMID: 31019933
PMCID: PMC6462657
DOI: 10.21037/atm.2019.01.09

Editorial

Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

Jens Juul Holst. Ann Transl Med. 2019 Mar.

. 2019 Mar;7(5):83.

doi: 10.21037/atm.2019.01.09.

Author

Jens Juul Holst¹

Affiliation

¹ Department of Biomedical Sciences and NNF center for Basic Metabolic Research, The Panum Institute, University of Copenhagen, Copenhagen, Denmark.

PMID: 31019933
PMCID: PMC6462657
DOI: 10.21037/atm.2019.01.09

No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has appeared on advisory boards for NovoNordisk.

Comment on

Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial.
Pratley RE, Aroda VR, Lingvay I, Lüdemann J, Andreassen C, Navarria A, Viljoen A; SUSTAIN 7 investigators. Pratley RE, et al. Lancet Diabetes Endocrinol. 2018 Apr;6(4):275-286. doi: 10.1016/S2213-8587(18)30024-X. Epub 2018 Feb 1. Lancet Diabetes Endocrinol. 2018. PMID: 29397376 Clinical Trial.

Cited by

Role of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists in Hypoglycemia.
Ja'arah D, Al Zoubi MS, Abdelhady G, Rabi F, Tambuwala MM. Ja'arah D, et al. Clin Med Insights Endocrinol Diabetes. 2021 Oct 17;14:11795514211051697. doi: 10.1177/11795514211051697. eCollection 2021. Clin Med Insights Endocrinol Diabetes. 2021. PMID: 34690504 Free PMC article. Review.
Is Weight Loss the Main Driver for A1C Improvement by Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists? A 2.5-Year Analysis in Real-World Clinical Practice.
Al-Badri M, Dhaver S, Hamdy O. Al-Badri M, et al. J Diabetes. 2025 Jan;17(1):e70054. doi: 10.1111/1753-0407.70054. J Diabetes. 2025. PMID: 39853913 Free PMC article.
A Comprehensive Review on GLP-1 Signaling Pathways in the Management of Diabetes Mellitus - Focus on the Potential Role of GLP-1 Receptors Agonists and Selenium among Various Organ Systems.
Barakat G, Assi G, Khalil H, El Khatib S. Barakat G, et al. Curr Diabetes Rev. 2024;21(2):e160424228945. doi: 10.2174/0115733998287178240403055901. Curr Diabetes Rev. 2024. PMID: 38629376 Review.
The incretin/glucagon system as a target for pharmacotherapy of obesity.
Del Prato S, Gallwitz B, Holst JJ, Meier JJ. Del Prato S, et al. Obes Rev. 2022 Feb;23(2):e13372. doi: 10.1111/obr.13372. Epub 2021 Oct 28. Obes Rev. 2022. PMID: 34713962 Free PMC article. Review.

References

1. Davies MJ, D’Alessio DA, Fradkin J, et al. Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2018;41:2669-701. 10.2337/dci18-0033 - DOI - PMC - PubMed
1. Holst JJ. The Physiology of Glucagon-like Peptide 1. Physiol Rev 2007;87:1409-39. 10.1152/physrev.00034.2006 - DOI - PubMed
1. Zhang Y, Sun B, Feng D, et al. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 2017;546:248-53. 10.1038/nature22394 - DOI - PMC - PubMed
1. Drucker DJ, Habener JF, Holst JJ. Discovery, characterization, and clinical development of the glucagon-like peptides. J Clin Invest 2017;127:4217-27. 10.1172/JCI97233 - DOI - PMC - PubMed
1. Kjems LL, Holst JJ, Volund A, et al. The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on beta-Cell Sensitivity in Type 2 and Nondiabetic Subjects. Diabetes 2003;52:380-6. 10.2337/diabetes.52.2.380 - DOI - PubMed

Publication types

Actions
Actions

LinkOut - more resources

Full Text Sources

[1] Davies MJ, D’Alessio DA, Fradkin J, et al. Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2018;41:2669-701. 10.2337/dci18-0033 - DOI - PMC - PubMed

[2] Davies MJ, D’Alessio DA, Fradkin J, et al. Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2018;41:2669-701. 10.2337/dci18-0033 - DOI - PMC - PubMed

[3] Holst JJ. The Physiology of Glucagon-like Peptide 1. Physiol Rev 2007;87:1409-39. 10.1152/physrev.00034.2006 - DOI - PubMed

[4] Holst JJ. The Physiology of Glucagon-like Peptide 1. Physiol Rev 2007;87:1409-39. 10.1152/physrev.00034.2006 - DOI - PubMed

[5] Zhang Y, Sun B, Feng D, et al. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 2017;546:248-53. 10.1038/nature22394 - DOI - PMC - PubMed

[6] Zhang Y, Sun B, Feng D, et al. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 2017;546:248-53. 10.1038/nature22394 - DOI - PMC - PubMed

[7] Drucker DJ, Habener JF, Holst JJ. Discovery, characterization, and clinical development of the glucagon-like peptides. J Clin Invest 2017;127:4217-27. 10.1172/JCI97233 - DOI - PMC - PubMed

[8] Drucker DJ, Habener JF, Holst JJ. Discovery, characterization, and clinical development of the glucagon-like peptides. J Clin Invest 2017;127:4217-27. 10.1172/JCI97233 - DOI - PMC - PubMed

[9] Kjems LL, Holst JJ, Volund A, et al. The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on beta-Cell Sensitivity in Type 2 and Nondiabetic Subjects. Diabetes 2003;52:380-6. 10.2337/diabetes.52.2.380 - DOI - PubMed

[10] Kjems LL, Holst JJ, Volund A, et al. The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on beta-Cell Sensitivity in Type 2 and Nondiabetic Subjects. Diabetes 2003;52:380-6. 10.2337/diabetes.52.2.380 - DOI - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

Affiliation

Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

Author

Affiliation

Conflict of interest statement

Comment on

Similar articles

Cited by

References

Publication types

LinkOut - more resources

Full Text Sources