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. 2018 Nov 27;2(4):yty134.
doi: 10.1093/ehjcr/yty134. eCollection 2018 Dec.

A case report: haemodynamic instability due to true dynamic left ventricular outflow tract obstruction and systolic anterior motion following resuscitation: reversal of haemodynamics on supportive veno-arterial extracorporeal membrane oxygenation

Affiliations

A case report: haemodynamic instability due to true dynamic left ventricular outflow tract obstruction and systolic anterior motion following resuscitation: reversal of haemodynamics on supportive veno-arterial extracorporeal membrane oxygenation

Christina Stolzenburg Oxlund et al. Eur Heart J Case Rep. .

Abstract

Background: Obstruction of the left ventricular outflow tract (LVOT) as seen in hypertrophic cardiomyopathy is a dynamic condition with a wide range of clinical presentations and symptoms.

Case summary: We report the use of veno-arterial extracorporeal membrane oxygenation in a female patient who was resuscitated after out-of-hospital cardiac arrest. Soon after admission the patient developed critical haemodynamic compromise due to severe obstruction of the left ventricle outflow tract and systolic anterior motion (SAM) of the mitral valve. Veno-arterial extracorporeal membrane oxygenation restored haemodynamics and was weaned after 4 days without any haemodynamic compromise due to SAM. The patient was discharged from the intensive care unit at Day 13, and after 3 days at the coronary care unit, she was discharged to ambulatory follow-up with no sequelae.

Discussion: Veno-arterial extracorporeal membrane oxygenation restored haemodynamic stability in this patient with dynamic severe LVOT obstruction following cardiac arrest.

Keywords: Case report; Mitral regurgitation (MR); Obstruction of the left ventricle outflow tract; Systolic anterior motion (SAM); Veno-arterial extracorporeal membrane oxygenation.

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Figures

Figure 1
Figure 1
Transoesophageal echocardiographic systolic long-axis images. (A and B) Acquired before, and (C and D) Immediately after initiation of veno-arterial extracorporeal membrane oxygenation. (A) White arrow shows severe systolic anterior motion and (B) left ventricular outflow tract obstruction causing severe mitral regurgitation (red arrow). After initiation of veno-arterial extracorporeal membrane oxygenation systolic anterior motion, left ventricular outflow tract obstruction and mitral regurgitation disappeared.

References

    1. Maron BJ, Maron MS.. Hypertrophic cardiomyopathy. Lancet 2013;381:242–255. - PubMed
    1. Howell N, Bradlow W.. Surgical management of left ventricular outflow obstruction in hypertrophic cardiomyopathy. Echo Res Pract 2015;2:R37–R44. - PMC - PubMed
    1. Bonacchi M, Maiani M, Harmelin G, Sani G.. Intractable cardiogenic shock in stress cardiomyopathy with left ventricular outflow tract obstruction: is extra-corporeal life support the best treatment? Eur J Heart Fail 2009;11:721–727. - PubMed
    1. Elliott PM, Gimeno JR, Tome MT, Shah J, Ward D, Thaman R, Mogensen J, McKenna WJ.. Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. Eur Heart J 2006;27:1933–1941. - PubMed
    1. Bach DS. Subvalvular left ventricular outflow obstruction for patients undergoing aortic valve replacement for aortic stenosis: echocardiographic recognition and identification of patients at risk. J Am Soc Echocardiogr 2005;18:1155–1162. - PubMed

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