A ratiometric fluorescence platform based on boric-acid-functional Eu-MOF for sensitive detection of H2O2 and glucose

Abstract

A Eu-metal organic framework (Eu-MOF) probe with dual-emission was reported for the ratiometric fluorescence detection of H₂O₂ and glucose. Because of the special nucleophilic reaction between boric group and H₂O₂, Eu³⁺ and 5-boronobenzene-1,3-dicarboxylic acid (BBDC) were selected to synthesize the functional MOF probe via a simple one-pot solvothermal method. The Eu-MOF shows dual-emission at 370 and 623 nm with the single excitation at 270 nm due to the energy transfer efficiency change for antenna effect procedure. After addition of H₂O₂, the red emission of Eu-MOF weakened and the blue emission enhances immediately under 270 nm irradiation, so the ratiometric fluorescence detection is established. Moreover, the obvious color change for visual measuring of H₂O₂ and glucose is illustrated to reveal the merit of Eu-MOF probe. The proposed method was demonstrated to be highly sensitive and selective for H₂O₂ and glucose, with the low detection limits of 0.0335 and 0.0643 μM, respectively. The established boric-acid-functional Eu-MOF sensing platform was proved as the powerful probe for H₂O₂ and the metabolites involved in H₂O₂-generating reaction.

Keywords: Boric acid group; Eu-MOF; Glucose; H(2)O(2); Ratiometric detection.