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Clinical Trial
. 2019 May-Jun;33(3):881-888.
doi: 10.21873/invivo.11554.

Effectiveness of a 12-month Exercise Intervention on Physical Activity and Quality of Life of Breast Cancer Survivors; Five-year Results of the BREX-study

Heidi Penttinen  1 , Meri Utriainen  2 , Pirkko-Liisa Kellokumpu-Lehtinen  3 , Jani Raitanen  4   5 , Harri Sievänen  4 , Riku Nikander  4 , Carl Blomqvist  2 , Riikka Huovinen  6 , Leena Vehmanen  2 , Tiina Saarto  2
Affiliations
Clinical Trial

Effectiveness of a 12-month Exercise Intervention on Physical Activity and Quality of Life of Breast Cancer Survivors; Five-year Results of the BREX-study

Heidi Penttinen et al. In Vivo. 2019 May-Jun.

Abstract

Background/aim: This is a report of the 5-year quality of life (QoL) findings of the BREX-study (n=444).

Patients and methods: A 12-month exercise intervention was arranged shortly after adjuvant treatments. Physical activity (PA) was assessed by PA diary, physical performance by a 2- km walking test, QoL by the EORTC QLQC30 and BR-23 questionnaires, fatigue by the FACIT-Fatigue scale and depression by the Beck's 13-item depression scale (BDI).

Results: Participants who improved their PA from baseline to 5-year follow-up were more likely to improve their global health score (RRR=1.02, p=0.016), physical (RRR=1.02, p=0.009), social (RRR=1.03, p=0.013), role functioning (RRR=1.03, p=0.005), and fatigue (RRR=1.02, p=0.002). An improved 2-km walking test was associated to improved global health, physical and role functioning, body image, future perspectives, and fatigue (p=0.011, p<0.001, p=0.001, p=0.021, p=0.012 and p=0.003). No significant difference between the groups was found.

Conclusion: Improvement in PA or physical performance yields a positive change in QoL of breast cancer patients.

Keywords: Breast cancer; exercise; quality of life; rehabilitation.

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Conflict of interest statement

The Authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1. Flow chart.
See this image and copyright information in PMC

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