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. 1987 Feb;325(6106):683-8.
doi: 10.1038/325683a0.

A T-cell receptor gamma/CD3 complex found on cloned functional lymphocytes

J Borst, R J van de Griend, J W van Oostveen, S L Ang, C J Melief, J G Seidman, R L Bolhuis

A T-cell receptor gamma/CD3 complex found on cloned functional lymphocytes

J Borst et al. Nature. 1987 Feb.

Abstract

Cloned blood lymphocytes that do not express the alpha- and beta-chains of the T-cell receptor show MHC-unrestricted cytotoxicity. These cells carry the gamma-protein, disulphide-linked either to another molecule or to itself, and associated with the CD3 complex. These observations may help to solve the mystery posed by the discovery of the gamma gene.

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