New Approaches and Trials in Pediatric Transfusion Medicine

Abstract

Blood transfusions are frequently lifesaving, but there is growing awareness of their associated infectious and noninfectious adverse events. Patient blood management advocates for judicious use of transfusions and considerations of alternatives to correct anemia or achieve hemostasis. Several transfusion practices, either already implemented or under investigation, aim to further improve the safety of transfusions. An enduring challenge in pediatric and neonatal transfusion practice is that studies typically focus on adults, and findings are extrapolated to younger patients. This article aims to summarize some of the newer developments in transfusion medicine with a focus on the neonatal and pediatric population.

Keywords: Blood substitutes; Hemoglobin-based oxygen carriers; Pathogen reduction technology; Pediatric transfusion practice; Platelet additive solutions.