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Case Reports
. 2019 May-Jun;36(3):236-238.
doi: 10.4103/lungindia.lungindia_111_16.

Atypical carcinoid tumor of the lung: A rare entity

Rajiv Garg  1 , Rahul Kumar  1 , Pradyumn Singh  2 , Silpa Kshetrimayum  1
Affiliations
Case Reports

Atypical carcinoid tumor of the lung: A rare entity

Rajiv Garg et al. Lung India. 2019 May-Jun.

Abstract

Carcinoids account for approximately 2% of all lung tumors, and the atypical carcinoids (ACs) are much rarer than typical carcinoid. Here, we report a rare case of AC tumor of the lung. A 50-year-old female patient presented with left-sided chest pain for 1 year, cough for 6 months, and loss of appetite for 6 months. Contrast-enhanced computed tomography scan of the thorax revealed an ill-defined heterogeneously enhancing soft-tissue attenuation lesion in the mediastinum following which transthoracic biopsy was done. Histomorphology and immunohistochemistry were consistent with AC, a neuroendocrine tumor. Combination chemotherapy consisting of cisplatin and etoposide was administered as initial chemotherapy.

Keywords: Atypical carcinoid; intrathoracic mass; neuroendocrine tumor.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Contrast-enhanced computed tomography scan of the thorax showing that the lesion is encasing branches of the arch of the aorta completely and the arch of the aorta partially
Figure 2
Figure 2
Histopathology of atypical carcinoid showing tissue infiltration by a tumor disposed in nests and trabeculae. The tumor cells are polygonal with moderately pleomorphic nuclei, granular chromatin, and moderate amount of eosinophilic cytoplasm. Mitotic figures (3/10 high-power fields) and apoptotic bodies are evident
Figure 3
Figure 3
Immunochemistry of atypical carcinoid positive for chromogranin
See this image and copyright information in PMC

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