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Case Reports
. 2019 Aug;38(8):e172-e174.
doi: 10.1097/INF.0000000000002348.

First Case Report of Intraventricular Tigecycline in a Neonate With Extensively Drug-resistant Acinetobacter baumannii Ventriculitis

Rathna Pratheep  1 , Somosri Ray  1 , Kanya Mukhopadhyay  1 , Vikas Gautam  2 , Nusrat Shafiq  3 , Sourabh Dutta  1 , Shiv Sajan Saini  1 , Anmol Bhatia  4
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Case Reports

First Case Report of Intraventricular Tigecycline in a Neonate With Extensively Drug-resistant Acinetobacter baumannii Ventriculitis

Rathna Pratheep et al. Pediatr Infect Dis J. 2019 Aug.

Abstract

Multidrug-resistant and extensively drug-resistant Acinetobacter baumannii infections have been increasing as a cause of healthcare-associated infections in the neonatal age group. In this report, we describe a 27-week, 1028 g, preterm neonate with extensively drug-resistant A. baumannii infection complicated by ventriculitis who did not respond to intravenous and intraventricular colistin but did respond after intraventricular tigecycline. This is the first case report describing the use of intraventricular tigecycline in a neonate with ventriculitis.

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