Regeneration of alveolar ridge defects. Consensus report of group 4 of the 15th European Workshop on Periodontology on Bone Regeneration

Søren Jepsen¹, Frank Schwarz², Luca Cordaro³, Jan Derks⁴, Christoph H F Hämmerle⁵, Lisa J Heitz-Mayfield⁶, Federico Hernández-Alfaro⁷, Henny J A Meijer⁸, Nadja Naenni⁵, Alberto Ortiz-Vigón⁹, Bjarni Pjetursson¹⁰, Gerry M Raghoebar¹¹, Stefan Renvert¹², Isabella Rocchietta¹³, Mario Roccuzzo¹⁴, Ignacio Sanz-Sánchez⁹, Massimo Simion¹⁵, Cristiano Tomasi⁴, Leonardo Trombelli¹⁶, Istvan Urban¹⁷

Affiliations

¹ Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany.
² Department of Oral Surgery and Implantology, Carolinum, Johann Wolfgang Goethe-University, Frankfurt, Germany.
³ Department of Periodontics and Prosthodontics, Policlinico Umberto I, Eastman Dental Hospital, Rome, Italy.
⁴ Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
⁵ Clinic of Fixed and Removable Prosthodontics and Dental Material Science, University of Zürich, Zurich, Switzerland.
⁶ International Research Collaborative - Oral Health and Equity, School of Anatomy, Physiology and Human Biology, University of Western Australia, Perth, Western Australia, Australia.
⁷ Department of Oral and Maxillofacial Surgery, International University of Catalonia, Barcelona, Spain.
⁸ Department of Oral and Maxillofacial Surgery and Department of Implant Dentistry, University Medical Center Groningen, Groningen, The Netherlands.
⁹ ETEP (Etiology and Therapy of Periodontal Diseases) Research Group, University Complutense, Madrid, Spain.
¹⁰ Department of Reconstructive Dentistry, University of Iceland, Reykjavik, Iceland.
¹¹ Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
¹² Oral Health Sciences, Kristianstad University, Kristianstad, Sweden.
¹³ Department of Periodontology, Eastman Dental Institute, UCL, London, UK.
¹⁴ Division of Maxillofacial Surgery, University of Torino, Torino, Italy.
¹⁵ Department of Periodontology, University of Milan, Milan, Italy.
¹⁶ Research Centre for the Study of Periodontal and Peri-implant Diseases University of Ferrara, Ferrara, Italy.
¹⁷ Graduate Implant Dentistry, Loma Linda University, Loma Linda, California.

PMID: 31038223
DOI: 10.1111/jcpe.13121

Free article

Regeneration of alveolar ridge defects. Consensus report of group 4 of the 15th European Workshop on Periodontology on Bone Regeneration

Søren Jepsen et al. J Clin Periodontol. 2019 Jun.

Free article

. 2019 Jun:46 Suppl 21:277-286.

doi: 10.1111/jcpe.13121.

Authors

Affiliations

¹ Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany.
² Department of Oral Surgery and Implantology, Carolinum, Johann Wolfgang Goethe-University, Frankfurt, Germany.
³ Department of Periodontics and Prosthodontics, Policlinico Umberto I, Eastman Dental Hospital, Rome, Italy.
⁴ Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
⁵ Clinic of Fixed and Removable Prosthodontics and Dental Material Science, University of Zürich, Zurich, Switzerland.
⁶ International Research Collaborative - Oral Health and Equity, School of Anatomy, Physiology and Human Biology, University of Western Australia, Perth, Western Australia, Australia.
⁷ Department of Oral and Maxillofacial Surgery, International University of Catalonia, Barcelona, Spain.
⁸ Department of Oral and Maxillofacial Surgery and Department of Implant Dentistry, University Medical Center Groningen, Groningen, The Netherlands.
⁹ ETEP (Etiology and Therapy of Periodontal Diseases) Research Group, University Complutense, Madrid, Spain.
¹⁰ Department of Reconstructive Dentistry, University of Iceland, Reykjavik, Iceland.
¹¹ Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
¹² Oral Health Sciences, Kristianstad University, Kristianstad, Sweden.
¹³ Department of Periodontology, Eastman Dental Institute, UCL, London, UK.
¹⁴ Division of Maxillofacial Surgery, University of Torino, Torino, Italy.
¹⁵ Department of Periodontology, University of Milan, Milan, Italy.
¹⁶ Research Centre for the Study of Periodontal and Peri-implant Diseases University of Ferrara, Ferrara, Italy.
¹⁷ Graduate Implant Dentistry, Loma Linda University, Loma Linda, California.

PMID: 31038223
DOI: 10.1111/jcpe.13121

Abstract

Background and aims: Bone augmentation procedures to enable dental implant placement are frequently performed. The remit of this working group was to evaluate the current evidence on the efficacy of regenerative measures for the reconstruction of alveolar ridge defects.

Material and methods: The discussions were based on four systematic reviews focusing on lateral bone augmentation with implant placement at a later stage, vertical bone augmentation, reconstructive treatment of peri-implantitis associated defects, and long-term results of lateral window sinus augmentation procedures.

Results: A substantial body of evidence supports lateral bone augmentation prior to implant placement as a predictable procedure in order to gain sufficient ridge width for implant placement. Also, vertical ridge augmentation procedures were in many studies shown to be effective in treating deficient alveolar ridges to allow for dental implant placement. However, for both procedures the rate of associated complications was high. The adjunctive benefit of reconstructive measures for the treatment of peri-implantitis-related bone defects has only been assessed in a few RCTs. Meta-analyses demonstrated a benefit with regard to radiographic bone gain but not for clinical outcomes. Lateral window sinus floor augmentation was shown to be a reliable procedure in the long term for the partially and fully edentulous maxilla.

Conclusions: The evaluated bone augmentation procedures were proven to be effective for the reconstruction of alveolar ridge defects. However, some procedures are demanding and bear a higher risk for post-operative complications.

Keywords: barrier membrane; biomaterials; bone augmentation; bone regeneration; bone replacement graft; complications/adverse events; consensus statement; dental implants; elevation; guided bone regeneration; peri-implantitis; ridge augmentation; sinus floor.

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Regeneration of alveolar ridge defects. Consensus report of group 4 of the 15th European Workshop on Periodontology on Bone Regeneration

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Regeneration of alveolar ridge defects. Consensus report of group 4 of the 15th European Workshop on Periodontology on Bone Regeneration

Authors

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Abstract

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