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. 1987;304(4):97-9.

[Effect of exogenous gangliosides on the metabolism of inositol compounds in chick neurons in primary culture]

[Article in French]
B Ferret, R Massarelli, L Freysz, H Dreyfus
  • PMID: 3103879

[Effect of exogenous gangliosides on the metabolism of inositol compounds in chick neurons in primary culture]

[Article in French]
B Ferret et al. C R Acad Sci III. 1987.

Abstract

A mixture of exogenous gangliosides at 10(-8) M and 10(-5) M concentration added to the medium of chick neurons stimulates the metabolism of inositol compounds. Notably the incorporation of [3H] myo-inositol is increased in phosphatidylinositol and in inositol triphosphate. Gangliosides, hence, by increasing the production of second messengers might regulate the phosphorylation processes of neuronal proteins.

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