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Comment

. 2019 May 1;176(5):410-411.

doi: 10.1176/appi.ajp.2019.19010044.

Explaining Naltrexone's Interference With Ketamine's Antidepressant Effect

Michael Wang, Adam Kaplin¹

Affiliations

Affiliation

¹ Department of Psychiatry and Behavioral Sciences (Wang, Kaplin) and Department of Neurology and Neurosurgery (Kaplin), Johns Hopkins University School of Medicine, Baltimore; Department of Molecular Microbiology and Immunology, Johns Hopkins University School of Public Health, Baltimore (Wang).

PMID: 31039639
DOI: 10.1176/appi.ajp.2019.19010044

Comment

Explaining Naltrexone's Interference With Ketamine's Antidepressant Effect

Michael Wang et al. Am J Psychiatry. 2019.

. 2019 May 1;176(5):410-411.

doi: 10.1176/appi.ajp.2019.19010044.

Authors

Michael Wang, Adam Kaplin¹

Affiliation

¹ Department of Psychiatry and Behavioral Sciences (Wang, Kaplin) and Department of Neurology and Neurosurgery (Kaplin), Johns Hopkins University School of Medicine, Baltimore; Department of Molecular Microbiology and Immunology, Johns Hopkins University School of Public Health, Baltimore (Wang).

PMID: 31039639
DOI: 10.1176/appi.ajp.2019.19010044

No abstract available

Keywords: Antidepressants; Depression; Drug Interactions; Ketamine; Naltrexone; Opioid.

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Comment in

Rigorous Translational Models Are Key to Studying Ketamine's Antidepressant Mechanism: Response to Wang and Kaplin.
Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF. Heifets BD, et al. Am J Psychiatry. 2019 May 1;176(5):412. doi: 10.1176/appi.ajp.2019.19010044r. Am J Psychiatry. 2019. PMID: 31039633 No abstract available.

Comment on

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism.
Williams NR, Heifets BD, Blasey C, Sudheimer K, Pannu J, Pankow H, Hawkins J, Birnbaum J, Lyons DM, Rodriguez CI, Schatzberg AF. Williams NR, et al. Am J Psychiatry. 2018 Dec 1;175(12):1205-1215. doi: 10.1176/appi.ajp.2018.18020138. Epub 2018 Aug 29. Am J Psychiatry. 2018. PMID: 30153752 Free PMC article. Clinical Trial.

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