Can IL-1 be used as a target for osteoarthritis?

Chao Cheng^{1

2}, Jian Tian³, Fangjie Zhang⁴

Affiliations

¹ Department of Orthopaedics, Yiyang Central Hospital, Yiyang, China.
² Clinical Medical Technology Demonstration Base for Minimally Invasive and Digital Orthopaedics in Hunan Province, Yiyang, China.
³ Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.
⁴ Department of Emergency Medicine, Xiangya Hospital, Central South University, Changsha, China zhangfj11@163.com.

PMID: 31040118
DOI: 10.1136/annrheumdis-2019-215513

Comment

Can IL-1 be used as a target for osteoarthritis?

Chao Cheng et al. Ann Rheum Dis. 2020 Jul.

. 2020 Jul;79(7):e88.

doi: 10.1136/annrheumdis-2019-215513. Epub 2019 Apr 30.

Authors

Chao Cheng^{1

2}, Jian Tian³, Fangjie Zhang⁴

Affiliations

¹ Department of Orthopaedics, Yiyang Central Hospital, Yiyang, China.
² Clinical Medical Technology Demonstration Base for Minimally Invasive and Digital Orthopaedics in Hunan Province, Yiyang, China.
³ Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.
⁴ Department of Emergency Medicine, Xiangya Hospital, Central South University, Changsha, China zhangfj11@163.com.

PMID: 31040118
DOI: 10.1136/annrheumdis-2019-215513

No abstract available

Keywords: cytokines; disease activity; hand osteoarthritis; pharmacokinetics.

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Conflict of interest statement

Competing interests: None declared.

Comment in

Response to: 'Can IL-1 be used as a target for osteoarthritis?' by Cheng et al.
Kloppenburg M, Levesque M. Kloppenburg M, et al. Ann Rheum Dis. 2020 Jul;79(7):e89. doi: 10.1136/annrheumdis-2019-215612. Epub 2019 Jun 27. Ann Rheum Dis. 2020. PMID: 31248854 No abstract available.

Comment on

Phase IIa, placebo-controlled, randomised study of lutikizumab, an anti-interleukin-1α and anti-interleukin-1β dual variable domain immunoglobulin, in patients with erosive hand osteoarthritis.
Kloppenburg M, Peterfy C, Haugen IK, Kroon F, Chen S, Wang L, Liu W, Levy G, Fleischmann RM, Berenbaum F, van der Heijde D, Bansal P, Wittoek R, Feng S, Fang Y, Saltarelli M, Medema JK, Levesque MC. Kloppenburg M, et al. Ann Rheum Dis. 2019 Mar;78(3):413-420. doi: 10.1136/annrheumdis-2018-213336. Epub 2018 Dec 14. Ann Rheum Dis. 2019. PMID: 30552176 Free PMC article. Clinical Trial.

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Can IL-1 be used as a target for osteoarthritis?

Affiliations

Can IL-1 be used as a target for osteoarthritis?

Authors

Affiliations

Conflict of interest statement

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