Natural history of nonalcoholic steatohepatitis/nonalcoholic fatty liver disease-hepatocellular carcinoma: Magnitude of the problem from a hepatology clinic perspective

Delia D'Avola^{1

2}, Ismail Labgaa^{1

3}, Augusto Villanueva^{1

4}

Affiliations

¹ Division of Liver Diseases, Liver Cancer Program, Department of Medicine Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai New York NY.
² Liver Unit and Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (Ciberehd) Clínica Universidad de Navarra Pamplona Spain.
³ Department of Visceral Surgery University Hospital of Lausanne (CHUV) Lausanne Switzerland.
⁴ Division of Hematology and Medical Oncology, Department of Medicine Icahn School of Medicine at Mount Sinai New York NY.

Review

Delia D'Avola et al. Clin Liver Dis (Hoboken). 2016.

. 2016 Oct 27;8(4):100-104.

doi: 10.1002/cld.579. eCollection 2016 Oct.

Delia D'Avola^{1

2}, Ismail Labgaa^{1

3}, Augusto Villanueva^{1

4}

¹ Division of Liver Diseases, Liver Cancer Program, Department of Medicine Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai New York NY.
² Liver Unit and Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (Ciberehd) Clínica Universidad de Navarra Pamplona Spain.
³ Department of Visceral Surgery University Hospital of Lausanne (CHUV) Lausanne Switzerland.
⁴ Division of Hematology and Medical Oncology, Department of Medicine Icahn School of Medicine at Mount Sinai New York NY.

No abstract available

Figures

1. Younossi ZM, Stepanova M, Afendy M, Fang Y, Younossi Y, Mir H, et al. Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin Gastroenterol Hepatol 2011;9:524–530.e1; quiz e60. - PubMed
1. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease: meta‐analytic assessment of prevalence, incidence, and outcomes. Hepatology 2016;64:73–84. - PubMed
1. Welsh JA, Karpen S, Vos MB. Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988‐1994 to 2007‐2010. J Pediatr 2013;162:496–500.e1. - PMC - PubMed
1. Singh S, Allen AM, Wang Z, Prokop LJ, Murad MH, Loomba R. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta‐analysis of paired‐biopsy studies. Clin Gastroenterol Hepatol 2015;13:643–654.e1‐9; quiz e39‐40. - PMC - PubMed
1. Dyson J, Jaques B, Chattopadyhay D, Lochan R, Graham J, Das D, et al. Hepatocellular cancer: the impact of obesity, type 2 diabetes and a multidisciplinary team. J Hepatol 2014;60:110–117. - PubMed