Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Apr;169(4):1737-9.
doi: 10.1128/jb.169.4.1737-1739.1987.

2',3'-Dialdehyde of ATP: a specific, irreversible inhibitor of component A3 of the methylreductase system of Methanobacterium thermoautotrophicum

2',3'-Dialdehyde of ATP: a specific, irreversible inhibitor of component A3 of the methylreductase system of Methanobacterium thermoautotrophicum

P E Rouvière et al. J Bacteriol. 1987 Apr.

Abstract

Among 17 purine and ATP derivatives tested, 3 were found to totally inhibit the methyl coenzyme M methylreductase system of Methanobacterium thermoautotrophicum at a concentration of 5 mM; these derivatives were 8-azido-ATP, alpha, beta-thio-ADP and 2',3'-dialdehyde-ATP. 2',3'-Dialdehyde-ATP specifically and irreversibly bound to component A3 of the methylreductase system during ATP activation of the system.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Biochim Biophys Acta. 1969 Dec 30;192(3):420-9 - PubMed
    1. J Bacteriol. 1978 Sep;135(3):851-7 - PubMed
    1. J Biol Chem. 1980 Mar 10;255(5):1891-5 - PubMed
    1. Arch Biochem Biophys. 1980 Sep;203(2):630-41 - PubMed
    1. J Bacteriol. 1985 Apr;162(1):61-6 - PubMed

Publication types

MeSH terms

LinkOut - more resources