Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Jan 16:386:1-9.
doi: 10.1016/s0021-9673(01)94578-9.

Liquid chromatographic method for the determination of 3,4-dihydroxyphenylethylene glycol and 3,4-dihydroxymandelic acid in plasma

B M Eriksson, B A Persson

Liquid chromatographic method for the determination of 3,4-dihydroxyphenylethylene glycol and 3,4-dihydroxymandelic acid in plasma

B M Eriksson et al. J Chromatogr. .

Abstract

A method is described for the simultaneous determination of the deaminated catecholamine metabolites 3,4-dihydroxyphenylethylene glycol (DOPEG) and 3,4-dihydroxymandelic acid (DOMA) in plasma by liquid chromatography with amperometric detection. The compounds are extracted from plasma by adsorption on alumina, then separated on a reversed-phase column coated with tributyl phosphate as the stationary liquid phase. It is a simple and selective method that permits the determination of basal levels of DOPEG and DOMA in plasma with a relative standard deviation of 3%.

PubMed Disclaimer

LinkOut - more resources