Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Feb 1;13(1):410.
doi: 10.4081/oncol.2019.410. eCollection 2019 Jan 14.

Advances in pancreatic cancer biomarkers

Syed Hasan  1 , Rojymon Jacob  1 , Upender Manne  1 , Ravi Paluri  1
Affiliations

Advances in pancreatic cancer biomarkers

Syed Hasan et al. Oncol Rev. .

Abstract

Biomarkers play an essential role in the management of patients with invasive cancers. Pancreatic ductal adenocarcinoma (PDC) associated with poor prognosis due to advanced presentation and limited therapeutic options. This is further complicated by absence of validated screening and predictive biomarkers for early diagnosis and precision treatments respectively. There is emerging data on biomarkers in pancreatic cancer in past two decades. So far, the CA 19-9 remains the only approved biomarker for diagnosis and response assessment but limited by low sensitivity and specificity. In this article, we aim to review current and future biomarkers that has potential serve as critical tools for early diagnostic, predictive and prognostic indications in pancreatic cancer.

Keywords: Pancreatic cancer; biomarkers.

PubMed Disclaimer

References

    1. Ryan DP, Hong TS, Bardeesy N. Pancreatic Adenocarcinoma. N Engl J Med 2014;371:1039-49. - PubMed
    1. Simoes PK, Olson SH, Saldia A, Kurtz RC. Epidemiology of pancreatic adenocarcinoma. Chin Clin Oncol 2017;6:24. - PubMed
    1. Jemal A, Siegel R, Ward E, et al. Cancer Statistics, 2009. Cancer J Clin 2009;59:225-49. - PubMed
    1. American Cancer Society. What is pancreatic cancer? Available from: https://www.cancer.org/cancer/pancreaticcancer/about/what-is-pancreatic-...
    1. Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2014;136:E359-86. - PubMed