Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986;9(4):335-42.
doi: 10.1007/BF01800482.

Age-related differences in plasmalogen content of erythrocytes from patients with the cerebro-hepato-renal (Zellweger) syndrome: implications for postnatal detection of the disease

R J Wanders, Y R Purvis, H S Heymans, J A Bakkeren, G G Parmentier, J van Eldere, H Eyssen, H van den Bosch, J M Tager, R B Schutgens

Age-related differences in plasmalogen content of erythrocytes from patients with the cerebro-hepato-renal (Zellweger) syndrome: implications for postnatal detection of the disease

R J Wanders et al. J Inherit Metab Dis. 1986.

Abstract

Phosphatidylethanolamine plasmalogen levels were determined in erythrocytes from controls and 13 patients with the cerebro-hepato-renal (Zellweger) syndrome. It was found that in Zellweger patients 20 weeks of age or younger, erythrocyte phosphatidylethanolamine plasmalogen levels were lowered whereas in older patients (except in one) normal levels were found. The results obtained suggest a close relationship between the age of the patients at sampling and the phosphatidylethanolamine plasmalogen levels in their erythrocytes. A possible explanation for these findings and the implications for the postnatal detection of Zellweger syndrome are discussed.

PubMed Disclaimer

References

    1. Eur J Pediatr. 1984 Apr;142(1):10-5 - PubMed
    1. J Biol Chem. 1979 Nov 10;254(21):10896-900 - PubMed
    1. J Cell Biol. 1985 May;100(5):1789-92 - PubMed
    1. Clin Chim Acta. 1985 Oct 15;151(3):217-21 - PubMed
    1. Ann N Y Acad Sci. 1982;386:170-82 - PubMed

Publication types

LinkOut - more resources