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Review
. 2019 Apr;42(2):56-61.
doi: 10.18773/austprescr.2019.014. Epub 2019 Apr 1.

Drug-induced movement disorders

Stephen R Duma  1   2 , Victor Sc Fung  1   2
Affiliations
Review

Drug-induced movement disorders

Stephen R Duma et al. Aust Prescr. 2019 Apr.

Abstract

Many therapeutic and illicit drugs can cause movement disorders. Antipsychotics and antiemetics are most commonly implicated

The time of onset of the movement disorder may be acute, subacute, or chronic. The severity can range from mild to severe and life-threatening

Early recognition of a drug-induced movement disorder is essential to allow for prompt intervention. This includes stopping the offending drug, supportive care, and sometimes other pharmacological treatment

Keywords: dystonia; neuroleptic malignant syndrome; parkinsonism; serotonin syndrome; tardive dyskinesia.

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Conflict of interest statement

Victor Fung receives a salary from NSW Health, has received unrestricted research grants from Abbvie and Merz, is on advisory boards and has received travel grants from Abbvie, Allergan, Cavion, Ipsen, Merz, Praxis, Seqirus, Stada, Teva and UCB, and receives royalties from Health Press. Dr Duma has received a speaker honorarium from UCB.

Comment in

  • Drug-induced bruxism.
    Teoh L, Moses G. Teoh L, et al. Aust Prescr. 2019 Aug;42(4):121. doi: 10.18773/austprescr.2019.048. Epub 2019 Aug 1. Aust Prescr. 2019. PMID: 31427840 Free PMC article. No abstract available.

References

    1. Claxton KL, Chen JJ, Swope DM. Drug-induced movement disorders. J Pharm Pract 2007;20:415-29. 10.1177/0897190007310514 - DOI
    1. Malek N, Baker MR. Common toxidromes in movement disorder neurology. Postgrad Med J 2017;93:326-32. 10.1136/postgradmedj-2016-134254 - DOI - PubMed
    1. Caroff SN, Campbell EC. Drug-induced extrapyramidal syndromes: implications for contemporary practice. Psychiatr Clin North Am 2016;39:391-411. 10.1016/j.psc.2016.04.003 - DOI - PubMed
    1. Burkhard PR. Acute and subacute drug-induced movement disorders. Parkinsonism Relat Disord 2014;20 Suppl 1:S108-12. 10.1016/S1353-8020(13)70027-0 - DOI - PubMed
    1. Kipps CM, Fung VS, Grattan-Smith P, de Moore GM, Morris JG. Movement disorder emergencies. Mov Disord 2005;20:322-34. 10.1002/mds.20325 - DOI - PubMed

FURTHER READING

    1. Jamshidi N, Dawson A. The hot patient: acute drug-induced hyperthermia. Aust Prescr 2019;42:24-8. 10.18773/austprescr.2019.006 - DOI - PMC - PubMed

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