Nuclear (Bio)physics in the Embryo
- PMID: 31051102
- DOI: 10.1016/j.cell.2019.04.031
Nuclear (Bio)physics in the Embryo
Abstract
Deneke et al. (2019) discover that dynamic interactions of cell cycle and actomyosin contractility systems synchronize nuclear cleavages, generating a cytoplasmic flow that results in a spatially uniform distribution of zygotic nuclei in the early Drosophila embryo. This work underscores the importance of self-organizing mechanisms before the onset of zygotic transcription.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos.Cell. 2019 May 2;177(4):925-941.e17. doi: 10.1016/j.cell.2019.03.007. Epub 2019 Apr 11. Cell. 2019. PMID: 30982601 Free PMC article.
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