All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way
- PMID: 31051131
- DOI: 10.1016/j.stem.2019.04.013
All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way
Abstract
Recently in Cell, Berg et al. (2019) show that Hopx-expressing neural progenitor cells in the embryonic dentate gyrus contribute to dentate neurogenesis through the embryonic to adult stage, exhibiting a common transcriptomic and epigenomic signature and developmental dynamics. This finding suggests a continuous model for neurogenesis in the dentate gyrus.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis.Cell. 2019 Apr 18;177(3):654-668.e15. doi: 10.1016/j.cell.2019.02.010. Epub 2019 Mar 28. Cell. 2019. PMID: 30929900 Free PMC article.
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