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Review
. 2019 May;36(3):182-186.
doi: 10.1053/j.semdp.2019.04.011. Epub 2019 Apr 17.

Carbapenem-resistant Enterobacteriaceae: An emerging bacterial threat

Affiliations
Review

Carbapenem-resistant Enterobacteriaceae: An emerging bacterial threat

Joseph D Lutgring. Semin Diagn Pathol. 2019 May.

Abstract

The first reports of carbapenem resistance in Enterobacteriaceae isolates occurred in the early 1990s. Researchers published the first report of an isolate that produced Klebsiella pneumoniae carbapenemase in 2001. Since that time, carbapenemase-producing Enterobacteriaceae isolates have disseminated globally. Microbiology laboratories are integral to the control of carbapenem-resistant Enterobacteriaceae (CRE). Laboratories need to be able to identify CRE, identify possible therapeutic alternatives, and sometimes identify the type of mechanism responsible for the carbapenem-resistant phenotype. Knowledge of these tasks is essential for all clinical microbiology laboratorians.

Keywords: Antibiotic; CRE; Carbapenem; Enterobacteriaceae; Resistance.

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